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Histogenics Internship

Manufacturing Day!

12/21/2017

 
The facilities at the Lexington location manufacture collagen for use in both the scaffolds and the CT3 adhesive for the NeoCart product. In accordance with cGMPs (current Good Manufacturing Procedures), this site utilizes an ISO Class 8 clean room with proper gowning routine and a USP water purifier in order to produce a high quality product. 
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For scaffolds,  once the mixture is made it is freeze dried until it resembles something similar to styrofoam. This is then sliced to a 1.5 mm sample from which the NeoCart scaffold and several surrogates can  be harvested. For the CT3 adhesive, methylated collagen is mixed with PEG (premade) in order to create a biodegradable substance that will hold the NeoCart in place until the cartilage can be held in on its own.
At the left, we're getting on our gowns - even though this site is cleaner than a surgical room in a hospital, it's still more relaxed than the lab in Waltham.  Juliana and Hannah like science!

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    ​Andrew Carr
    Andrew Dembowski
    Gavin Garland

    We are seniors at SJP who are interested in science. Last summer, we participated in a two-week summer internship at Histogenics in Waltham.  Thanks so much to the Histogenics Company for making their time available to us, and especially chief technology officer Steve Kennedy, whose idea it was to make the experience possible.  Thank you!!

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  • Home
  • Student Research
    • Eel Grass Studies
    • Aquaponics Blog
    • Wind Energy Research
    • Deep Learning for BCI
    • Cloud Chamber Blog
    • And much more.. >
      • Bioluminesence
  • Lab Visits
    • Novartis Cambridge
    • Greentown Labs
    • MASS CEC
    • MIT Plasma Physics Center
    • Histogenics
    • US GreenBuild - Boston
  • Physics Olympics
    • Paper Airplanes
    • Glider Competition
  • Internships + More
    • Histogenics 2017